TRUNORMAL® CONTROLS - When Normal Isn’t Good Enough
This blog post was written by BioIVT, a CRO that enables smarter science and accelerates medical breakthroughs by delivering high-quality personalized biospecimen solutions and research services to life science and diagnostic industries. Their services are available on the Scientist.com marketplace.
BioIVT’s Center for NeuroExcellence provides unparalleled access to high-quality, ethically-sourced biospecimens. We aim to be the indispensable partner to neurology researchers worldwide, helping to accelerate discoveries and breakthroughs that transform the future of neurological healthcare.
Redefining ‘Normal’ in Neuroscientific Research
TruNormal® Controls
In neuroscientific research, the integrity of biospecimens is paramount. The common practice among numerous providers is to categorize their specimens as ‘normal’ in the absence of diagnosed neurological pathologies. However, such samples often fail to account for subclinical neurological manifestations or family history of neurological disorders. Using these samples for research carries the risk of unrecognized, aberrant biomarkers corrupting the data and research results.
Exclusivity
Unlike the typical ‘normal’ biospecimens from many suppliers, our TruNormal® samples come exclusively from donors who are genuinely normal, ensuring that researchers are equipped with samples that are not just labeled normal, but embody true neurological/psychiatric normalcy.
With the acquisition of PrecisionMed, BioIVT is now the world’s only supplier of TruNormal® biological samples. These samples can be matched to our banked diseased material when normal controls are required.
Our TruNormal® neuroscience samples are from donors with normal cognition, no history and no family history of significant neurological or neuropsychiatric disease and no neurological complaints.
Our TruNormal® donors range from 20 to 90 years old, supplying a broad spectrum of control samples for age-stratified research.
From Bench to Breakthrough: A Massive Repository at Your Fingertips
Gain an edge in biomedical research with our vast repository of biospecimens, which includes more than 35,000 TruNormal® samples and more than 113,000 diseased donor samples, providing you with exceptional resources for comparative studies and precise control matching.
Match with Precision: Age, Gender, Race/Ethnicity and More
TruNormal® Control Matching
Capitalize on the granularity of our demographic data to enhance the precision of your comparative analyses. Donor specifics like age, gender and race/ethnicity allow for refined control matching and comparative studies that mirror the demographic realities of disease prevalence, leading to more meaningful research conclusions.
Multiple Sample Types From the Same Donor
TruNormal® Precision
Strengthen your research precision with our repository’s multiple sample types from each donor for a streamlined, multi-omic approach. Uncover correlations and validate your findings with our extensive biospecimen collection. Rely on consistent data for cross-sample validation and detailed donor insights to conduct superior comparative studies.
Data-Rich Samples: Adding Clinical Depth to Biospecimen Analysis
TruNormal® Data
Our samples include detailed clinical data like MMSE and MoCA scores. This enhances sample relevance and offers a focused approach to research, stratification of cognitive abilities and insightful correlations charting the progression of neurologic conditions.
Longitudinal Samples: Your Time Machine to New Discoveries
TruNormal® Longitudinal Samples
Leverage the power of our longitudinal samples and data for in-depth biomedical research. Track disease progression, analyze treatment response and study intra-individual variability. Our repository is the largest private global source of longitudinally collected human CSF, offering a window into disease evolution and treatment efficacy.
Validated Biomarkers for Clear Conclusions
Most of our samples come with biomarker data that further solidify the integrity of your research. This allows you to enhance correlation studies, validate biomarker reliability and drive biomarker discovery. Uncover molecular disease pathways, build predictive models and streamline study design, all while confirming sample integrity.
Our Collection Process
Our meticulous, six-step collection process begins with the in-depth validation of our collection sites and ends with you owning your discoveries, free of royalties.
BioIVT’s Center for NeuroExcellence is constantly collecting samples with our predictive biobanking approach. Therefore, we have a robust inventory that is ready to ship immediately.
We partner with experienced clinical sites that undergo in-depth validation prior to onboarding and throughout the relationship. Our samples are of the highest possible quality and are ready to ship when you’re ready to receive them.