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Physically separate substances using liquid chromatography and mass spectrometry.

Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.

Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.

Develop and validate methods for synthesis and scale up of drug candidates.

Perform chemical structural changes to improve preclinical drug candidate.

Determine molecular structure, identify chemical impurities and validate sample integrity.

Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.

Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.

Find chemicals used for creating new compound chemotypes and HTS libraries.

Find targeted and broad collections of chemical compounds for high throughput screening and ADMET applications.